Epigenetic reprogramming of Toxoplasma sexual development in vitro, using the MORC/HDAC3 complex as a cornerstone.

Mohamed-Ali Hakimi received his PhD in plant molecular biology from the University of Grenoble Alpes (UGA), France, in 2000. After a postdoctoral internship at the Wistar Institute (UPENN, Philadelphia), he joined the French Institute of Public Health INSERM as a permanent scientist in 2004, where he currently serves as research director and leads a team at the Institute of Advanced Biosciences (Grenoble, France). His team is investigating the sophisticated epigenetic mechanisms that Toxoplasma gondii employs to profoundly alter host gene expression and remodel its own genome to evade immune defenses and promote transmission and lifelong persistence in diverse hosts.